Surgical Management of Gout-Complicated Humeral Nonunion A Case Report
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Abstract
Humeral shaft fractures may progress to nonunion despite operative management. We report a 50-year-old male with repeated surgical failure of a left humeral shaft fracture, found intraoperatively to have uric acid crystal deposition within the pseudoarthrosis site. The patient underwent implant removal, excision of the pseudoarthrosis, and rigid plate fixation augmented with an intramedullary fibular strut graft. At six months postoperatively, clinical evaluation demonstrated mechanical stability and satisfactory functional recovery. Although fibular strut grafting is not universally considered standard treatment for humeral nonunion, this case highlights its potential role in complex, biologically compromised nonunions associated with gout.
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References
1. Azar FM, Beaty JH, Canale ST, eds. Campbell’s Operative Orthopaedics. 14th ed. Philadelphia, PA: Elsevier; 2021.
2. Fink Barnes LA, Ruig DFH, Freibott CE, Rajfer R, Rosenwasser MP. Treatment of nonunions of the humeral shaft with nonvascularized fibular strut allograft: postoperative outcomes and review of a surgical technique. JSES Int. 2020;4(4):739-44. https://pubmed.ncbi.nlm.nih.gov/33345209 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738593 https://doi.org/10.1016/j.jseint.2020.08.013
3. Perez-Ruiz F, Dalbeth N, Bardin T. A review of uric acid, crystal deposition disease, and gout. Adv Ther. 2015;32(1):31-41. https://pubmed.ncbi.nlm.nih.gov/25533440 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311063 https://doi.org/10.1007/s12325-014-0175-z
4. Yadav SS. The use of a free fibular strut as a "biological intramedullary nail" for the treatment of complex nonunion of long bones. JB JS Open Access. 2018;3(2):e0050. https://pubmed.ncbi.nlm.nih.gov/30280135 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145563 https://doi.org/10.2106/JBJS.OA.17.00050
5. Jeon YS, Hwang DS, Hwang JM, Lee JK, Park YC. Pathological fracture of the femoral neck due to tophaceous gout: an unusual case of gout. Hip Pelvis. 2019;31(4):238-41. https://pubmed.ncbi.nlm.nih.gov/31824879 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892900 https://doi.org/10.5371/hp.2019.31.4.238
6. Liu F, Dong J, Zhou D, Kang Q, Xiong F. Gout is not associated with the risk of fracture: a meta-analysis. J Orthop Surg Res. 2019 Aug 27;14(1):272. https://pubmed.ncbi.nlm.nih.gov/31824879 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892900 https://doi.org/10.5371/hp.2019.31.4.238
7. Calvi M, Gnesutta A, Zabetta LC, et al. Case report of a tibial fracture in a patient suffering from gout: An atypical site, the importance of differential diagnosis. Radiol Case Rep. 2022;17(4):1180-4. https://pubmed.ncbi.nlm.nih.gov/35169424 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8829500 https://doi.org/10.1016/j.radcr.2022.01.005